One of the most heavily referenced sections of Segel’s work is his systematic categorization of enzyme inhibition. He provides distinct algebraic equations and diagnostic plots (such as Lineweaver-Burk and Eadie-Hofstee) for:
A: Biochemical Calculations: How to Solve Mathematical Problems in General Biochemistry , 2nd Edition, by Irwin H. Segel (1976).
When dealing with regulatory or allosteric enzymes, standard Michaelis-Menten kinetics fail. Segel dedicates significant space to sigmoidal kinetics, explaining:
